29, 30 OP downregulates several EGFR mediated pathways such as JAK STAT, PI3K Akt, and MAPK involved in cancer cell proliferation, metastasis, and tumour vascularization priligy 30 mg While in control cultures positive myogenin expression was seen in cell clusters, in beta GA treated cultures the myogenin immunoreactivity was detected in few, preferentially sparse cells